Lion's Mane Research We're Watching: Two New Trials on Attention, Memory, and Mood

If you follow our blog, you know we sell lion's mane — and we take the science behind it seriously. When new trials come out, we read them and share what they found and what they didn't. Two new ones caught our eye, so here's the straight version of both.

Trial 1: The Australian study on healthy adults (Bat et al., 2024)

What it did
A double-blind, randomized, placebo-controlled trial run in Australia. Healthy adults took 1.8 grams per day of lion's mane fruiting body extract — or a placebo — for 12 weeks, with working memory and attention measured along the way.

What they found
The lion's mane group showed significantly better working memory and attention than the placebo group by the end of the 12 weeks. The effect sizes were modest — an improvement, not a transformation.

The caveats
One honest flag: we haven't been able to get our hands on the full paper yet, so this summary comes from an independent review of the lion's mane research, not from us reading the study itself. Secondhand summaries are exactly where findings get stretched, so we're reporting this one carefully — and we'll update this post if we track down the full text. And as with any single trial: one study is a signal, not proof.

Trial 2: The People Science trial on adults with cognitive concerns (April 2026)

What it did
A randomized, double-blind, placebo-controlled trial run by People Science, Inc. Adults aged 40 to 75 who reported cognitive difficulty went through a one-week baseline, then took 2 grams per day of a lion's mane fruiting body and mycelial biomass blend — or a placebo — for 8 weeks. Cognitive performance was tested with a computerized battery, and sleep and wellbeing were tracked daily, all done remotely. 109 people were included in the final analysis (57 on lion's mane, 52 on placebo).

What they found
Compared with placebo, the lion's mane group showed significantly greater improvement in visual attention and working memory, plus faster improvements in subjective sleep quality, morning restedness, and mood. No adverse events were reported in the lion's mane group. The researchers' own summary word: "modestly."

The caveats — read these first
This study is a preprint — posted online for other scientists to read, but not yet peer-reviewed. That doesn't make it wrong, but it means it hasn't gone through the full checking process yet. The effects were modest, not dramatic. Everyone in the trial was an older adult who already reported cognitive difficulty, so it says nothing about what lion's mane does for healthy young adults. And all testing was remote, which introduces more variability than lab-based trials.

What this means for you

Honestly? For our products, nothing changes. Our Lion's Mane Mushroom Powder is here to support focus and mental clarity as part of your daily routine — that's what we stand behind. These trials tested different forms and doses of lion's mane in specific groups of people, so they tell us nothing about what our product does for any person or condition. We won't claim otherwise.

We'll keep following the research and reporting it the way we read it — the interesting parts and the limits. If follow-up work with larger groups and longer timelines comes along, you'll hear about it here first.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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